Physicians practicing ambulatory medicine have never had more opportunities to use Information technology to help them In their everyday practice. In parallel, evolving health care Industry dynamics are Increasing the need for clinical computer applications, which help Improve the quality, efficiency, and the cost-effectiveness of patient care. This article examines: (1) the Information needs of practicing physicians, (2) current and emerging technologies that can Improve clinical decision making at the point of care, and (3) the impact of these technologies on clinical quality, medical costs, and physician practice efficiency. The article uses patient case scenarios to Illustrate the emerging role of Information technology in patient care.