Intermittent Explosive DisorderEpidemiology, Diagnosis and Management
作者:
Rene L. Olvera,
期刊:
CNS Drugs
(ADIS Available online 2002)
卷期:
Volume 16,
issue 8
页码: 517-526
ISSN:1172-7047
年代: 2002
出版商: ADIS
关键词: Alpha 2 adrenoceptor agonists, therapeutic use;Antidepressants, adverse reactions;Antipsychotics, therapeutic use;Beta adrenoceptor antagonists, therapeutic use;Cognitive behavioural therapy;Intermittent explosive disorders, treatment;Phenytoin, therapeut
数据来源: ADIS
摘要:
Intermittent explosive disorder (IED) is characterised by discrete episodes of aggressive impulses that result in serious assaultive acts towards people or destruction of property. IED causes severe impairments in daily function. The diagnosis of IED should be made only after a thorough medical work-up. A structured or semi-structured diagnostic interview is helpful to ensure that comorbid and pre-existing conditions are considered.There is a lack of controlled trials of agents for the treatment of patients with IED, but there is evidence that mood stabilisers, antipsychotics, β-blockers, α2-agonists, phenytoin and antidepressants may be useful. Behavioural interventions may be valuable as part of the overall treatment of IED.
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