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Metformin and Moroxidine Determination With Cu (II)

 

作者: J.Martinez Calatayud,   P.Campíns Falcó,   yM.C. Pascual Marti.,  

 

期刊: Analytical Letters  （Taylor Available online 1985）
卷期: Volume 18, issue 11  

页码: 1381-1390

 

ISSN:0003-2719

 

年代: 1985

 

DOI:10.1080/00032718508066218

 

出版商: Taylor & Francis Group

 

关键词: Conductometric titration of biguanides;copper - biguanide complexes.

 

数据来源: Taylor

 

摘要:

Conductometric titrations of metformin and moroxidine are reported. The procedure is based on the copper-biguanide reaction which gives a pink soluble complex. Studies at several pH values and presence of NH3are carried out. NaOH-NH3(1:15) are added to 5 ml of biguanide aqueous solution and diluted to 60 ml and titrated with copper sulphate. Concentrations of metformin in 205x10−4-1,7x10−3M range are determined. Foreign species presence is studied too.

 

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