Morphological Observations of the Fetal Rat Spleen during Prolonged Gestation
作者:
James A. Thliveris,
Daniela Petriuk,
Judy E. Anderson,
Edmund E. Faridy,
期刊:
Cells Tissues Organs
(Karger Available online 1983)
卷期:
Volume 117,
issue 3
页码: 231-238
ISSN:1422-6405
年代: 1983
DOI:10.1159/000145792
出版商: S. Karger AG
关键词: Morphology;Fetal rat;Spleen;Prolonged gestation
数据来源: Karger
摘要:
The ultrastructure of splenic cells and frequency of cell types were examined in fetal rats during progesterone-induced (P23, 24, 25) and surgically-induced (S23, 24, 25) prolonged gestation, and compared to term (T) fetuses and newborn animals (N1 N2, N3). Statistical analysis revealed an increase in numbers of erythroblasts and a decrease in numbers of neutrophils in post-term fetuses distinct from that seen in term and newborn animals. However, there were also significant differences between the post-term groups: the frequency of erythrocytes and total number of cells were higher in the drug-treated group, despite similar splenic weights in the two. The results are interpreted as a response by the spleen (increased erythropoiesis) to fetal hypoxia, which is known to exist during prolonged gestation.
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