Mechanisms of Acute and Chronic Nephrotoxicity from Immunosuppressive Drugs
作者:
BennettWilliam M.,
期刊:
Renal Failure
(Taylor Available online 1996)
卷期:
Volume 18,
issue 3
页码: 453-460
ISSN:0886-022X
年代: 1996
DOI:10.3109/08860229609052816
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Cyclosporine and related compounds have dramatically improved the short-term success of solid organ transplantation. This paper outlines the pathophysiologic mechanisms of the nephrotoxicity of these compounds, highlighting relevant clinical and experimental work. It is hoped that as further understanding of these mechanisms evolves, rational therapeutic strategies will be available.
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