Optimization and application of the large volume on‐column introduction (LOCI) technique for capillary GC with preliminary on‐line capillary solvent distillation/concentration
作者:
Joseph F. Hiller,
Terry McCabe,
Paul L. Morabito,
期刊:
Journal of High Resolution Chromatography
(WILEY Available online 1993)
卷期:
Volume 16,
issue 1
页码: 5-12
ISSN:0935-6304
年代: 1993
DOI:10.1002/jhrc.1240160102
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: On‐column injection;On‐line injection;Large (100 μ) injections;Precision;Linearity;Carry‐over;Discrimination;Activity;Polar compounds;High boiling compounds;Environmental analyses
数据来源: WILEY
摘要:
AbstractThis report describes an on‐line capillary GC injection system which enables on‐column injection of a hundred or more microliters, and yields separations comparable with those obtained from on‐column injection of 1–2 microliters of solutions a hundred times more concentrated. Precision, carry‐over, linearity, and discrimination are comparable with those of classical sample‐introduction techniques. A selection of polar and high boiling compounds has been examined, and excellent peak shapes obtained for hundreds of injections. Initial results indicate that maintenance and long‐term reproducibility will also be comparable with those of classical techniques.The instrument utilizes a version of the large volume on‐column injector with solvent diversion described in an earlier communication, with the addition of a method for independent heating of the retention gap. This modification reduces the effects of activity in the retention gap and improves the capability of the technology to handle complex mixtures. It also increases reliability and system lifetime, fits readily into most GC ovens, is easily automated, and should be compatible with all capilla
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