Abstract:A Child with epidermolysis bullosa dystrophica, recessive type (EBDR) developed significant anemia at 9 years of age and was treated with long‐term transfuslon therapy. At age 17 he had symptoms of congestive heart failure secondary to dilated cardlomyopathy. Treatment with digoxin and vasodilators for the past year has failed to improve his cardiomyopathy significantly. Chronic iron overload and secondary hemosiderosis may have contributed to his problems, and we propose that chelation therapy be used in any child received long‐term transfusion ther