Anaesthesia‐induced dissociation between the circadian rhythms of blood pressure and heart rate
作者:
P. Cugini,
G. Delogu,
M.A. Casula,
L. Gatta,
C. Cascioli,
L. Di Palma,
期刊:
Journal of Interdisciplinary Cycle Research
(Taylor Available online 1991)
卷期:
Volume 22,
issue 4
页码: 333-340
ISSN:0022-1945
年代: 1991
DOI:10.1080/09291019109360118
出版商: Taylor & Francis Group
关键词: Anaesthesia;blood pressure;body temperature;chronobiology;circadian rhythm;monitoring
数据来源: Taylor
摘要:
The circadian rhythms of blood pressure (BP) and heart rate (HR) were documented in 30 patients for a 24‐hour period before and during the 24 hours that included unilateral surgery for senile cataract or retinal detachment. The patients were premedicated with diazepam. Anaesthesia was induced at a fixed time (09.00) in all patients with thiopentone, and muscle relaxation was with pancuronium. Maintenance was with enflurane in 15 patients and with fentanyl and droperidol in the rest. Though the intraoperative changes in haemodynamic parameters were dissimilar with the two types of maintenance agents, but both types had a similar effect on the circadian rhythms of blood pressure and heart rate. Whereas preoperatively the BP and HR circadian rhythms were nearly in phase, with their peaks in the late morning to early afternoon, the postoperative rhythms underwent a dissociation to a phase shift in the BP 24‐h pattern. The phase effect may be hypothetically attributed to direct pharmacological actions or to masking effects.
点击下载:
PDF (367KB)
返 回