Comparison of Antibodies as Molecular Recognition Elements for Biosensor Design
作者:
DianaL. Busha,
GarryA. Rechnitz,
期刊:
Analytical Letters
(Taylor Available online 1988)
卷期:
Volume 21,
issue 11
页码: 1947-1967
ISSN:0003-2719
年代: 1988
DOI:10.1080/00032718808059883
出版商: Taylor & Francis Group
关键词: Dinitrophenol;Monoclonal Antibodies;Membrane Electrode
数据来源: Taylor
摘要:
Antibodies are studied in terms of their properties as molecular recognition elements using an antigen monitoring biosensor as a means of examining sensitivity and selectivity. This approach requires only a small amount of antibody for study and is illustrated for a model system in which two monoclonal antibodies and one polyclonal antibody to 2,4-dinitrophenol are compared on the basis of their association constants and cross-reactivity patterns with heterologous haptens.
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