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Echocardiographic Functions and Blood Pressure Levels in Children and Young Adults from a Biracial PopulationThe Bogalusa Heart Study

 

作者: LUIS SOTO,   DAVID KIKUCHI,   RENE ARCILLA,   DANIEL SAVAGE,   GERALD BERENSON,  

 

期刊: The American Journal of the Medical Sciences  (OVID Available online 1989)
卷期: Volume 297, issue 5  

页码: 271-279

 

ISSN:0002-9629

 

年代: 1989

 

出版商: OVID

 

关键词: Blood Pressure;Hemodynamics;Echocardiography;Hypertension

 

数据来源: OVID

 

摘要:

M-mode echocardiograms were obtained on 651 healthy subjects, 7–22 years of age, whose diastolic blood pressure levels remained in the same height-, race-, and sex-specific decile during two biannual examinations. Echocardiographic measures of heart size and dynamics were compared across the total blood pressure distribution. Left ventricular stroke volume, cardiac output and ejection fraction, minor axis shortening, velocity of circumferential fiber shortening, and peripheral vascular resistance were correlated with blood pressure levels. There were positive correlations (p < .001) of cardiac output and stroke volume with both systolic and diastolic blood pressure levels. Left ventricular output and stroke volume were associated with measures of body size, especially height, weight, ponderal index, and body surface area (p < .001). The left ventricular output and stroke volume increased with age and with systolic blood pressure quintiles in the four race-sex groups. With adjustment for systolic blood pressure and measures of body size, white males had greater cardiac output (1.25 1/minute for ages 18–22 years, p = .01) and stroke volume than black males. Black males had higher peripheral resistance (4.5 mm Hg/(1/minute), p = .01) than whites. These results suggest that different hemodynamic mechanisms operate in the early phase of hypertension in blacks vs. whites in this population.

 

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