首页   按字顺浏览 期刊浏览 卷期浏览 Effect of Somatostatin and Dopaminergic Agents on Bovine Pituitary Phosphodiesterase Ac...
Effect of Somatostatin and Dopaminergic Agents on Bovine Pituitary Phosphodiesterase Activity

 

作者: Akio Nagasaka,   Hiroyoshi Hidaka,   Hifumi Nakagawa,   Akira Nakai,   Takako Ohyama,   Toshihiro Aono,   Rumi Masunaga,   Katsumi Iwase,  

 

期刊: Neuroendocrinology  （Karger Available online 1986）
卷期: Volume 43, issue 3  

页码: 410-415

 

ISSN:0028-3835

 

年代: 1986

 

DOI:10.1159/000124557

 

出版商: S. Karger AG

 

关键词: Somatostatin;Dopaminergic agent;Pituitary gland;Cyclic nucleotides;Cyclic nucleotide phosphodiesterase

 

数据来源: Karger

 

摘要:

The effects of somatostatin and dopaminergic agents on pituitary cyclic nucleotide phosphodiesterases that had been partially purified through DEAE cellulose column chromatography were studied. Somatostatin, .L-dopa, dopamine and CB-154(2-bromo-α-ergocriptine) competitively inhibited the pituitary cyclic AMP phosphodiesterase activity, especially that of the low Km enzyme. This inhibition was most potent in the case of somatostatin and CB-154

 

点击下载:  PDF (1192KB)



返 回