Innervation Densities of Inner and Outer Hair Cells of the Human Organ of Corti
作者:
Joseph B. Nadol, Jr.,
期刊:
ORL
(Karger Available online 1988)
卷期:
Volume 50,
issue 6
页码: 363-370
ISSN:0301-1569
年代: 1988
DOI:10.1159/000276014
出版商: S. Karger AG
关键词: Corti’s organ;Inner hair cells;Outer hair cells;Synapses;Neural degeneration
数据来源: Karger
摘要:
The innervation densities, i.e. the number of afferent endings per inner and outer hair cell, number of synaptic specializations per inner hair cell and the number of efferent endings per outer hair cell, were evaluated by serial section electron microscopy in the normal human inner ear and a case of Usher’s syndrome (retinitis pigmentosa and sen-sorineural hearing loss). There was a significant decrease in the innervation density in Usher’s syndrome as compared to normative controls, which could not be explained by the decrease in density of spiral ganglion cells. This was interpreted as suggesting a decrease in the number of neural processes and endings within the dendritic arborization of remaining spiral ganglion cells in this disor
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