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Synthesis of Some Sulfur Containing Tetrahydrobenzo[b] Thieno(Pyridines, Quinolines, Oxazines and Pyrimidines) as Possible Radioprotective and Antineoplastic Agents

 

作者: M.M. Ghorab,   O.M. Nassar,   A.Y. Hassan,  

 

期刊: Phosphorus, Sulfur, and Silicon and the Related Elements  （Taylor Available online 1998）
卷期: Volume 134, issue 1  

页码: 57-76

 

ISSN:1042-6507

 

年代: 1998

 

DOI:10.1080/10426509808545452

 

出版商: Taylor & Francis Group

 

关键词: Thieno(pyridine; quinoline; oxazine);radioprotective and antineoplastic agents

 

数据来源: Taylor

 

摘要:

Synthesis of novel benzothienopyridines, benzothienoquinoline, benzothienoxazines and benzothienopyrimidines utilizing 2-methyl-5,6,7,8-tetrahydro-4H-3,1-benzothienoxazine-4-one are reported. The structure of these compounds were confirmed by micro-analyses, IR,1H-NMR and mass spectrometry. Preliminary biological studies of some compounds showed a promising radioprotection and antineoplastic activities.

 

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