Creatinine Height Index and Lean Body Mass in Adult Patients With Insulin‐Dependent Diabetes Mellitus Followed for 7 Years From Onset
作者:
A.M. Rosenfalck,
O. Snorgaard,
T. Almdal,
C. Binder,
期刊:
Journal of Parenteral and Enteral Nutrition
(WILEY Available online 1994)
卷期:
Volume 18,
issue 1
页码: 50-54
ISSN:0148-6071
年代: 1994
DOI:10.1177/014860719401800150
出版商: SAGE Publications
数据来源: WILEY
摘要:
The 24‐hour urinary creatinine excretion value can be used as an index of protein nutrition; the creatinine height index and lean body mass can be estimated from this value. On the basis of longitudinally measured 24‐hour urinary creatinine excretions during the initial 7 years of type 1 diabetes in an incidence cohort of 147 adult patients, we studied creatinine height index and lean body mass and possible relationships to sequential measurements of glycated hemoglobin (HbA1c). The patients were divided into four groups according to their glycemic control during these 7 years: I, HbA1c8.9% (n = 35). One year after the onset of diabetes, height indices were as follows (% of normal values, median and quartiles): I, 104% (90 to 116); II, 101% (78 to 105); III, 121% (92 to 128); IV, 87% (78 to 109) ([IV]<[I to III];p<.05). During the following 6 years no significant differences in height index were observed among the four groups of patients at any point in time. Slightly higher calculated lean body mass values were found in the most well‐controlled patients, but otherwise no differences were found in lean body mass. It is concluded that, apart from the first year, indices of protein nutrition remain normal during the initial 7 years of type 1 diabetes, even in patients with poor glycemic control. (Journal of Parenteral and Enteral Nutrition18:50–54, 1994)
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