Congenital Mesoblastic Nephroma With HypercalcemiaPathogenetic Role of Prostaglandins
作者:
Loredana Vido,
Modesto Carli,
Gianfranco Rizzoni,
Lorenzo Calò,
Paolo Palma,
Anna Parenti,
Fabrizio Fusco,
期刊:
American Journal of Pediatric Hematology/Oncology
(OVID Available online 1986)
卷期:
Volume 8,
issue 2
页码: 149-152
ISSN:0192-8562
年代: 1986
出版商: OVID
关键词: Hypercalcemia;Mesoblastic nephroma;Prostaglandins
数据来源: OVID
摘要:
A case of mesoblastic nephroma, hypercalcemia, and raised levels of prostaglandins in a 2-month-old female infant is reported. Plasma parathyroid hormone (PTH) was normal and urinary prostaglandins were raised. During surgery a prostaglandin arteriovenous gradient was demonstrated. A large quantity of PGE was extracted from the tumor by radioimmunoassay after incubation. Both blood calcium and urinary prostaglandins returned to normal after nephrectomy. These results show that this tumor produced prostaglandins, the mediators of hypercalcemia in this patient.
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