Disorders in Peripheral Arterial System in Asymptomatic Elderly: Plethysmographic Semiology at Rest, during Postural, Effort and Pharmacological Tests
作者:
C. Strozzi,
G. Cocco,
A. Destro,
G. Padovan,
V. Abbasciano,
S. Tosatti,
期刊:
Gerontology
(Karger Available online 1979)
卷期:
Volume 25,
issue 1
页码: 24-35
ISSN:0304-324X
年代: 1979
DOI:10.1159/000212317
出版商: S. Karger AG
关键词: Peripheral arterial system;Asymptomatic elderly;Plethysmography;Nitroglycerin;Metaproterenol test;Vasodilation;Vasoconstriction
数据来源: Karger
摘要:
The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The plethysmogram (PTG) was recorded from the forefinger of the left hand at rest, during two postural tests (+ 45° arm-up and –45° arm-down), after physical work, and during the infusion of nitroglycerin and the β-agonist metaproterenol. 50% of the subjects presented a normal PTG under basal conditions. However, pathological PTGs were recorded after the various tests: 23.3% with the arm-up test, 6.6% with the arm-down test, 52% with the effort test, 31% with the nitroglycerin test and 73.9% with the metaproterenol test. Clearly, the effort and metaproterenol tests are pathological in the majority of cases, both tests inducing physiologically vasodilation and increase in the peripheral pulse. The arm-down test, which usually induces vasoconstriction, is almost always normal. Since the percentage of pathological responses to the nitroglycerin test is significantly smaller than that to the effort and metaproterenol tests, it is concluded that the vascular changes induced by aging are primarily functional, at least in asymptomatic subjects. Aging more negatively influences the vasodilating than the vasoconstricting abi
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