Brugada SyndromeA Decade of Progress
作者:
C.,
Antzelevitch P.,
Brugada J.,
Brugada R.,
Brugada W.,
Shimizu I.,
Gussak A.,
期刊:
Circulation Research: Journal of the American Heart Association
(OVID Available online 2002)
卷期:
Volume 91,
issue 12
页码: 1114-1118
ISSN:0009-7330
年代: 2002
出版商: OVID
关键词: ventricular tachycardia;ventricular fibrillation;arrhythmia;sudden death
数据来源: OVID
摘要:
Abstract—The Brugada syndrome has gained wide recognition throughout the world and today is believed to be responsible for 4% to 12% of all sudden deaths and ≈20% of deaths in patients with structurally normal hearts. The incidence of the disease is on the order of 5 per 10 000 inhabitants and, apart from accidents, is the leading cause of death of men under the age of 50 in regions of the world where the inherited syndrome is endemic. This minireview briefly summarizes the progress made over the past decade in our understanding of the clinical, genetic, cellular, ionic, and molecular aspects of this disease.
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