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Some Age-Related Structural Peculiarities of Fractionated Chromatin

 

作者: I.Yu. Khilobock,   T.G. Mozzhukhina,   V.N Chabanny,   S.N. Kadura,  

 

期刊: Gerontology  （Karger Available online 1983）
卷期: Volume 29, issue 1  

页码: 9-18

 

ISSN:0304-324X

 

年代: 1983

 

DOI:10.1159/000213089

 

出版商: S. Karger AG

 

关键词: Rat;Liver;Small intestinal mucosa;Repressed chromatin;Active chromatin;Nucleosomes

 

数据来源: Karger

 

摘要:

Thermal denaturation and electrophoretic mobility of liver and small intestinal mucosa fractionated chromatin and the DNA of chromatin fractions have been studied in young and old rats. During aging, the thermostability of chromatin increased, electrophoretic mobility of mono-, di-, and trinucleosomal fragments decreased at the expense of increased repeated length of nucleosomal DNA.

 

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