首页   按字顺浏览 期刊浏览 卷期浏览 A non‐parametric graphical representation of the relationship between survival and the ...
A non‐parametric graphical representation of the relationship between survival and the occurrence of an event: Application to responder versus non‐responder bias

 

作者: Richard Simon,   Robert W. Makuch,  

 

期刊: Statistics in Medicine  (WILEY Available online 1984)
卷期: Volume 3, issue 1  

页码: 35-44

 

ISSN:0277-6715

 

年代: 1984

 

DOI:10.1002/sim.4780030106

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: Clinical trial;Non‐parametric survival function estimator;Time‐dependent covariate Transient state analysis

 

数据来源: WILEY

 

摘要:

AbstractReports of cancer clinical trials often attempt to evaluate whether tumour response is associated with prolonged survival. Proper analysis requires accounting for the time‐dependent nature of response status. We review a valid and relatively simple method of significance testing for this problem, and develop a corresponding non‐parametric method for displaying the association between survival and occurrence of response. The new method applies to many other clinical problems involving representation and the association between survival and the occurrence of an event. We illustrate the method with data from two clinical tri

 

点击下载:  PDF (639KB)



返 回