A model for mercuric ion reduction in recombinantEscherichia coli
作者:
George P. Philippidis,
Janet L. Schottel,
Wei‐Shou Hu,
期刊:
Biotechnology and Bioengineering
(WILEY Available online 1991)
卷期:
Volume 37,
issue 1
页码: 47-54
ISSN:0006-3592
年代: 1991
DOI:10.1002/bit.260370108
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractPlasmid‐encoded mercuric reduction involves transfer of Hg2+across the cellular envelope and reduction to Hg0by the cytoplasmic mercuric reductase using NADPH. A mathematical model was developed for the binding and transfer of Hg2+by transport proteins and the subsequent reduction of Hg2+. The values of the model parameters were determined using experimental data. The derived rate expressions were similar to the previously experimentally determined ones. The model predicted that a differential amplification of the transport protein relative to mercuric reductase expression levels may enhance the Hg2+reduction rate in whole cell
点击下载:
PDF
(699KB)
返 回