BIOTRANSFORMATIONS A survey of the Biotransformations of Drugs and Chemicals in Animals Volume 1 Edited by David R. Hawkins Huntingdon Research Centre The series haspbeen devised to provide an up-to-date survey of the literature on the biotransformation of pharmaceuticals pesticides food additives and environmental and industrial chemicals in animals. The objective is to provide a comprehensive database which will allow an increased awareness of patterns in species differences and the influence of chemical structure on biotransformation pathways. The ability to predict biotransformation is the ultimate goal which could contribute to the discovery and development of new products. The material has been collated into chemical classes but an additional feature is the definition and allocation of key functional groups for each compound.The functional groups selected are those commonly associated with biotransformation. Indexing these functional groups provides ready access to reports on compounds containing common structural features. An additional index of biotransformation processes and compound names further increases the accessibility of relevant information. Contents Key Functional Groups; An Overview; Hydrocarbons Aliphatic Aromatic (Monocyclic/Bicyclic); Polycyclic Aromatic Hydrocarbons Unsubstituted Hydroxylated Derivatives Substituted; Alkenes Halogenoalkanes and Halogenoalkenes Alkenes (Epoxides) Halogenoalkanes Halogenoalkenes; Acyclic Functional Compounds; Substituted Monocyclic Aromatic Compounds Halogenoaryl Phenols Nitroaryl/NitrophenoIs Carboxylic Acids/Esters Ketones Aryl Amines Benzhydryls Arylalkylamines; Miscellaneous Aromatics; Heterocycles Monocyclic Five-membered Monocyclic Six-membered Monocyclic Seven-membered BicycWTricyclic; Functional Nitrogen Compounds; Nitrosamines; Amino Acids and Peptides; Steroids; Miscellaneous Inorganic and Organometallic Pyrethroids Organophosphorus Compounds Sulphur Compounds; Compound Index; Key Functional Group Index; Reaction Type Index ISBN 0 85186 157 1 February 1989 Hardcover 511 pages Price S75.00 ($150.00) CARBOHYDRATE CHEMISTRY Vol.20 Part I Senior Reporter Neil R. Williams Birkbeck College University of London Since Volume 14 Carbohydrate Chemistryhas been divided into two parts Part I -Mono- Di- and Tri-saccharides and their derivatives.Part 2 -Macromolecules. From Volume 19 Part I was renamed Monosaccharides Disaccharides and Specific Oligosaccharides. Carbohydrate Chemistry Volume 20 (Part I)provides a review of the literature published during 1986. Brief Contents Introduction and General Aspects; Free Sugars Glycosides and Disaccharides; Oligosaccharides; Ethers and Anhydro-sugars; Acetals; Esters; Halogeno-Sugars; Amino-sugars; Miscellaneous Nitrogen Derivatives; Thio-sugars; Deoxy-sugars; Unsaturated Derivatives; Branched-chain Sugars; Aldosuloses Dialdoses and Diuloses; Sugar Acids and Lactones; Inorganic Derivatives; Alditols and Cyclitols; Antibiotics; Nucleosides; NMR Spectroscopy and Conformational Features; Other Physical Methods; Separatory and Analytical Methods; Synthesis of Enantiomerically Pure Non-carbohydrate Compounds; Author Index.ROYAL ISBN 0 85186 242 X Published 1988 SOCIETYOF Hardcover 315pp Price E70.00 ($147.00) CHEMISTR’I For further information To Order please write to RSC Members are entitled to a please write to Royal Society of Chemistry Distribution discount on most RSC publications and Royal Society of Chemistry Centre Blackhorse Road Letchworth should write to lnformation Sales and Promotion department Herts SG6 1HN. U.K. The Membership Manager Services Thomas Graham House or telephone (0462) 672555 quoting Royal Society of Chemistry Science Park your credit card details. Thomas Graham House Milton Road We can now accept AccessNisal Science Park Milton Road Cambridge CB4 4WF.U.K. MasterCard/Eurocard. Cambridge CB4 4WF. U.K. NUCLEAR MAGNETIC RESONANCE Volume 17 Senior Reporter G. A. Webb University of Surrey Nuclear Magnetic Resonance Volume 7 7provides a review of the literature published between June 1986 and May 1987. Brief Contents N.M.R. Books and Reviews; Theoretical and Physical Aspects of Nuclear Shielding; Applications of Nuclear Shielding; Theoretical Aspects of Spin-Spin Couplings; Nuclear Spin Relaxation in Liquids; Solid State N.M.R.; Multiple Pulse N.M.R.; Natural Macromolecules; Synthetic Macromolecules; Conformational Analysis; Nuclear Magnetic Resonance of Living Systems; Oriented Molecules; Heterogeneous Systems. Nuclear Magnetic Resonance Volume 7 7 contains a foreword by the Senior Reporter and a detailed contents list.Each chapter includes extensive references. ISBN 0 85186 402 3 Specialist Periodical Report (1988) Hardcover 546 pages Price E1lO.OO ($220.00) PHOTOCHEMISTRY Volume 19 Senior Reporters D. Bryce-Smith and A. Gilbert University of Reading Photochemistry Volume 79 provides a review of the literature published between July 1986 and June 1987. Brief Contents Part l Physical Aspects of Photochemistry Photophysical Processes in Condensed Phases. Part /I Photochemistryof lnorganic and Organometallic Compounds The Photochemistry of Transition-metal Complexes; The Photochemistry of Transition-metal Organometallic Compounds; The Photochemistry of Compoundsof the Main Group Elements. Part 111Organic Aspects of Photochemistry:Photolysisof Carbonyl Compounds; Enone Cycloadditions and Rearrangements Photoreactions of Dienones and Quinones; Photochemistry of Alkenes Alkynes and Related Compounds; Photochemistry of Aromatic Compounds; Photo-reduction and -oxidation; Photoreactions of Compounds containing Heteroatoms other than Oxygen; Photoelimination.Part IV Polymer Photochemistry Part V Photochemical Aspects of Solar Energy Conversion Photochemistry Volume 79 has an author index and each chapter includes extensive references. “All photochemists remain in the debt of the hard-working crew of scientists who generate these reviews and the production editors who maintain very high standards of presentation.” lAPS Newsletter reviewing Volume 75. ISBN 0 85186 175 X Specialist Periodical Report (1988) Hardcover 598 pages Price E110.00 ($220.00) GENERAL AND SYNTHETIC METHODS Volume 10 Senior Reporter G.Pattenden University of Nottingham Generaland Synthetic Methods Volume 70provides a critical and comprehensive summary and assessment of the literature published from January to December 1985. Brief Contents Saturated and Unsaturated Hydrocarbons; Aldehydes and Ketones; Carboxylic Acids and Derivatives; Alcohols Halogeno-Compounds and Ethers; Amines Nitriles and other Nitrogen-containing Functional Groups; Organometallics in Synthesis; Saturated Carbocyclic Ring Synthesis; Saturated Heterocyclic Ring Synthesis; Highlights in Total Synthesis of Natural Products; Reviews on General Synthetic Methods.General and Synthetic Methuds Volume 70 contains an introduction by the Senior Reporter and is indexed by author. ROYAL SOCIETYOF CHEMISTRY ISBN 0 85186 914 9 Hardcover 648pages Specialist Periodical Report (1988) Price E125.00 ($250.00) Information Services For further information please write to Royal Society of Chemistry Sales and Promotion department Thomas Graham House Science Park Milton Road Cambridge CB4 4WF. U.K. To Order please write to Royal Society of Chemistry Distribution Centre Blackhorse Road Letchworth Herts SG6 1HN. U.K. or telephone (0462) 672555 quoting your credit card details. We can now accept AccessNisal MasterCard/Eurocard. RSC Members are entitled to a discount on most RSC publications and should write to The Membership Manager Royal Society of Chemistry Thomas Graham House Science Park Milton Road Cambridge CB4 4WF. U.K. PRINTED IN GREAT BRITAIN BY THE UNIVERSITY PRESS CAMBRIDGE