Case ReportHypertension in Cushing's Syndrome
作者:
HIROMICHI SUZUKI,
HIROTAKA SHIBATA,
MAROHITO MURAKAMI,
HIDETOMO NAKAMOTO,
KAZUOKI KONDO,
TAKAO SARUTA,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1992)
卷期:
Volume 303,
issue 5
页码: 329-332
ISSN:0002-9629
年代: 1992
出版商: OVID
关键词: Adrenal tumor;Cortisol;Cushing's syndrome;Glucocorticoid;Hypertension
数据来源: OVID
摘要:
Pathogenesis of hypertension in Cushing's syndrome has remained controversial. A 56-year-old Japanese man with Cushing's syndrome due to adrenal carcinoma has been followed up for more than 6 years. During the followup period, left adrenalectomy and hemi-hepatectomy due to metastatic lesion were performed. Blood pressure, serum cortisol, and urinary excretion of 17-OHCS, as well as other routine biochemicals, have been measured periodically. These data revealed that there is a marked correlation between the levels of blood pressure and serum cortisol or urinary excretion of 17-OHCS. This finding suggests that cortisol production by tumor is a determinant factor in hypertension in Cushing's syndrome.
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