Pregnancy Rate following Normal versus Abnormal Hysterosalpingography Findings: A Meta-Analysis
作者:
Jacques W.M. Maas,
Johannes L.H. Evers,
Gerbenter Riet,
Alphons G.H. Kessels,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1997)
卷期:
Volume 43,
issue 2
页码: 79-83
ISSN:0378-7346
年代: 1997
DOI:10.1159/000291826
出版商: S. Karger AG
关键词: Hysterosalpingography;Infertility;Meta-analysis;Pregnancy rate;Prognostic value
数据来源: Karger
摘要:
A computerized Medline search was conducted, to assess the prognostic value of hysterosalpingography (HSG) and the probability of pregnancy after normal versus abnormal HSG findings. A total of 13 studies turned out to be eligible, reporting on 3,277 women. 15% of women with an abnormal HSG and 32% of women with a normal HSG achieved pregnancy. Sensitivities and specificities of the studies were heterogeneous. The pooled odds ratio was 3 (95% CI: 2.3–3.4). Its ROC Curve shows that, at the operating point yielding the lowest number of misclassifications, a sensitivity of 63% and a specificity of 62% is achieved. Seven studies reported unilateral and bilateral obstruction. Odds ratios were 2 (95% CI: 1.5–2.6) and 19 (95% CI: 7.5–46.5) respectively. So, overall, HSG has a low prognostic value, the outcome of HSG adds little to predicting the occurrence of pregnancy. However, when HSG shows bilateral obstruction, the chance of getting pregnant is only minimal.
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