Diversity of Some Gene Frequencies in European and Asian Populations
作者:
Alessandra Farabegoli,
Guido Barbujani,
期刊:
Human Heredity
(Karger Available online 1990)
卷期:
Volume 40,
issue 6
页码: 313-321
ISSN:0001-5652
年代: 1990
DOI:10.1159/000153954
出版商: S. Karger AG
关键词: Gene frequencies;Spatial autocorrelation;Isolation by distance;Genetic drift;Gene flow
数据来源: Karger
摘要:
Genetic variation at the phosphoglucomutase-1 (PGM) and acid phosphatase (ACP) loci, in 160 and 120 European and Asian populations, respectively, is described by spatial autocorrelation statistics and directional variograms. Short-distance patterns of gene frequencies correspond to those predicted by models of isolation by distance, but long-range differentiation of populations is observed as well. A possible role of climatic selection in maintaining the PGM polymorphism is supported by the north-south orientation of the gradient for that locus, but not by biochemical evidence. By and large, the observed patterns of gene frequencies seem to reflect a combination of demographic processes, subdivision and isolation of local populations among them.
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