Changes in Intestinal Alpha-Methyl-D-Glucoside Uptake due to Pregnancy and Lactation in Rats
作者:
R.M. Prieto,
M. Ferrer,
J.A. Tur,
期刊:
Digestion
(Karger Available online 1996)
卷期:
Volume 57,
issue 1
页码: 16-21
ISSN:0012-2823
年代: 1996
DOI:10.1159/000201307
出版商: S. Karger AG
关键词: Pregnancy;Lactation;Small intestine;Glucose;Intestinal absorption
数据来源: Karger
摘要:
Uptake of α-methyl-D-glucoside, a nonmetabolizable glucose analogue, by everted intestinal sleeves was studied in virgin, pregnant and lactating rats. The animals showed an increase in jejunal and ileal tissue mass, mucosal mass, nominal surface area, and enzymatic activities. No changes were observed in the carrier affinity throughout the breeding stages. Nevertheless there was a significant increase in glucose carrier density (Vmax) per unit of length of jejunum and ileum in pregnant and lactating animals. Integrating the results obtained, an increased overall ability to transport hexoses by nonspecific adaptation can be observed in breeding stages
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