Role of Hyperthermic Perfusion in the Treatment of Limb Osteogenic Sarcoma
作者:
R. Cavaliere,
F. Di Filippo,
F.S. Santori,
L. Piarulli,
S. Carlini,
A. Calabrò,
M. Pagliarin,
F. Cavaliere,
P. Cerulli,
G. Monticelli,
期刊:
Oncology
(Karger Available online 1987)
卷期:
Volume 44,
issue 1
页码: 1-5
ISSN:0030-2414
年代: 1987
DOI:10.1159/000226433
出版商: S. Karger AG
关键词: Hyperthermia;Hyperthermic perfusion;Osteogenic sarcoma
数据来源: Karger
摘要:
The role of hyperthermic perfusion (HP) for the treatment of limb osteogenic sarcoma was evaluated in 76 patients. Twelve patients were treated with HP alone, and a 5- and 10-year survival rate of 25.5% was obtained. When amputation was systematically associated to HP (12 patients), a 5- and 10-year survival rate of 50.9% was achieved. Twenty-seven patients were treated with hyperthermic antiblastic perfusion (HAP) followed by amputation 4 weeks later. With this treatment, the 5- and 10-year actuarial rates rose to 71.4 and 65%, respectively, with a 5-year disease-free survival rate of 67.4%. Fifteen patients were treated with HAP followed by an ‘en bloc’ resection and bone reconstruction. The 5- and 10-year actuarial survival rate obtained was 63.5% with a 5-year disease-free survival rate of 53.6%. These results seem to indicate that HAP permits carrying out conservative rather than ablative surgery for the treatment of limb osteogenic sarc
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