Lysosomal Enzyme Activities Among Chinese: Leukocyte α-Galactosidase and β-Galactosidase
作者:
Y.-K. Xu,
W.G. Ng,
期刊:
Human Heredity
(Karger Available online 1988)
卷期:
Volume 38,
issue 2
页码: 76-82
ISSN:0001-5652
年代: 1988
DOI:10.1159/000153762
出版商: S. Karger AG
关键词: Chinese;α-Galactosidase;β-Galactosidase;Leukocytes;Fabry’s disease;GM1gangliosidosis;Carrier detection
数据来源: Karger
摘要:
α-Galactosidase and β-galactosidase activities have been determined in leukocyte preparations from 100 randomly selected Chinese adults. For α-galactosidase, two groups with low activities were identified: group I consisted of 3 females having activities below 40% of normal, and group II consisted of 5 males and 1 female with activities about 60% of normal. Family studies suggested that these low α-galactosidase activities are genetically determined. Only 1 individual was found to have about 50% of normal β-galactosidase activity; presumably he is a carrier for β-galactosidase deficiency (GM1 gangliosid
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