Fetal Serum Ferritin and Cobalamin in Red Blood Cell Isoimunisation
作者:
Anthony Abbas,
Kypros Nicolaides,
期刊:
Fetal Diagnosis and Therapy
(Karger Available online 1995)
卷期:
Volume 10,
issue 5
页码: 297-300
ISSN:1015-3837
年代: 1995
DOI:10.1159/000264247
出版商: S. Karger AG
关键词: Ferritin;Cobalamin;Red blood cell isoimmunisation
数据来源: Karger
摘要:
Fetal and maternal serum ferritin and cobalamin concentrations were examined in 40 red blood cell-isoimmunised pregnancies undergoing cordocentesis at 18–38 weeks of gestation and the values were compared to those of normal pregnancies. In the red blood cell-isoimmunised pregnancies, the fetal serum ferritin concentration was increased and the cobalamin concentration was decreased, whereas maternal serum ferritin was decreased and cobalamin was not significantly different from normals. There was a significant association between the degree of fetal anaemia and the increase in fetal serum ferritin concentration, but not with fetal serum cobalamin. This study suggests that fetal haemolytic anaemia is associated with iron overload and cobalamin deficienc
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