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Quality Control of Pharmaceutical Aspirin Powder by Near-Infrared Reflectance Spectra and Multivariate Analysis

 

作者: Yulin Ren,   Zhuoyong Zhang,   Yuqiu Ren,   Wei Li,   Sidong Liu,  

 

期刊: Spectroscopy Letters  （Taylor Available online 1997）
卷期: Volume 30, issue 8  

页码: 1699-1711

 

ISSN:0038-7010

 

年代: 1997

 

DOI:10.1080/00387019708006753

 

出版商: Taylor & Francis Group

 

关键词: Near infrared spectrometry;diffuse reflectance;multivariate analysis;quality control;acetyl salicylic acid

 

数据来源: Taylor

 

摘要:

Quality control of pharmaceutical aspirin powder was studied using first order differential near-infrared diffuse reflectance spectra and four standard multivariate methods, hierarchical clustering analysis, stepwise clustering analysis, principal components analysis, and stepwise discrimination. The qualified, inferior, and fake pharmaceutical aspirin powders of independent samples can be distinguished by the multivariate analysis methods based on the reflectance spectra. The proposed methods are reliable, fast and nondestructive.

 

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