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Brain tumours and the occurrence of severe invasive basal cell carcinoma in first degree relatives with Gorlin syndrome

 

作者: EvansD. Gareth R.,   BirchJillian M.,   OrtonClive I.,  

 

期刊: British Journal of Neurosurgery  （Taylor Available online 1991）
卷期: Volume 5, issue 6  

页码: 643-646

 

ISSN:0268-8697

 

年代: 1991

 

DOI:10.3109/02688699109002890

 

出版商: Taylor&Francis

 

关键词: Basal cell carcinoma;Gorlin syndrome;medulloblastoma;radiotherapy

 

数据来源: Taylor

 

摘要:

We describe the occurrence of a medulloblastoma and an astrocytoma in successive generations of a family with the Gorlin syndrome. The appearance of thousands of invasive basal cell carcinomata after craniospinal irradiation led to the death of one patient from intracranial involvement.

 

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