Delegates were updated on the most recent outcomes data for 2 of the newer thrombolytics posing a threat to alteplase [t-PA], at the 48th Annual Scientific Session of the American College of Cardiology [New Orleans, US; March 1999]. Data presented from InTIME II*and ASSENT 2**showed that lanoteplase [nPA] and tenecteplase [TNK-tPA] have similar effects to alteplase on mortality in patients with acute myocardial infarction (MI).