首页   按字顺浏览 期刊浏览 卷期浏览 Synthesis of the antiinflammatory prodrug RS‐42169‐14C
Synthesis of the antiinflammatory prodrug RS‐42169‐14C

 

作者: Howard Parnes,   Glenn T. Huang,  

 

期刊: Journal of Labelled Compounds and Radiopharmaceuticals  （WILEY Available online 1995）
卷期: Volume 36, issue 1  

页码: 51-56

 

ISSN:0362-4803

 

年代: 1995

 

DOI:10.1002/jlcr.2580360106

 

出版商: John Wiley&Sons, Ltd.

 

关键词: RS‐42619‐14C;HWA 486‐14C;cycloaddition;antiinflammatory

 

数据来源: WILEY

 

摘要:

AbstractA facile synthesis of the antiinflammatory agent RS‐42169‐14C, based on a carbonation/cycloaddition sequence is described. The product was obtained in 36% yield from Ba14CO3at a specific activity of 52 mCi/mmole. The design of the six step sequence was such that pure intermediates were isolated by extractive workup, and only a single chromatographic purification was requi

 

点击下载:  PDF (281KB)



返 回