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L-β-Phenylalanine-125as an Ainino Acid Tolerance Test

 

作者: A. A. Hafiez,   Y. M. Megahed,   A. A. Ismail,   M. F. Abdel-Wahab,   R. A. Khater,  

 

期刊: Isotopenpraxis Isotopes in Environmental and Health Studies  （Taylor Available online 1978）
卷期: Volume 14, issue 3  

页码: 91-93

 

ISSN:0021-1915

 

年代: 1978

 

DOI:10.1080/10256017808622586

 

出版商: Taylor & Francis Group

 

关键词: blood;diagnosis;ingestion;inhibition;iodine 125;labelled compounds;metformin;nuclear medicine;phenylalanine;radioactivity;tracer techniques;uptake

 

数据来源: Taylor

 

摘要:

An amino acid tolerance lest is described using L-β-phenylalanine-125I as representative to L-amino acids. The change in radioactivity of the blood after giving a test dose of tagged L-β-phenylalanine was also investigated. L-β-phenylalanine-I125tolerance curves were found to be irreproducible when the test dose was given without a carrier. The addition of 2.5 g untagged phenylalanine as a carrier to the test dose allowed a reproducible and precise type of tolerance curves. Metformin in a dose of 0.5 g. t.d.s. for three days induced an inhibitory effect on, amin acids absorption in normal persons.

 

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