首页   按字顺浏览 期刊浏览 卷期浏览 Giant cell lichenoid dermatitis: A possible manifestation of sarcoidosis
Giant cell lichenoid dermatitis: A possible manifestation of sarcoidosis

 

作者: Lynne J. Goldberg,   Neil Goldberg,   Irving Abrahams,   David N. Silvers,   Wojciech Szaniawski,   Alan J. Halperin,  

 

期刊: Journal of Cutaneous Pathology  (WILEY Available online 1994)
卷期: Volume 21, issue 1  

页码: 47-51

 

ISSN:0303-6987

 

年代: 1994

 

DOI:10.1111/j.1600-0560.1994.tb00690.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

Giant cell lichenoid dermatitis is a recently described dermatosis thought to be an unusual lichenoid drug eruption. It is characterized by a generalized, pruritic, papulosquamous eruption sparing palms, soles, face and mucous membranes. Histopathologic findings include areas of epidermal hyperplasia and atrophy with focal vacuolar alteration of the basal layer, exocytosis and cytoid body formation. The dermis contains a band‐like, mononuclear cell infiltrate at the dermoepidermal junction with admixed cosinophils, plasma cells and large multinucleate cells. The histologic differential diagnosis includes infectious processes, sarcoidosis, lichen nitidus, lupus erythematosus and lichen planus. We report 3 patients with giant cell lichenoid dermatitis, one of whom was subsequently diagnosed as having sarcoidosis. Because giant cell lichenoid dermatitis may resemble sarcoidosis both clinically and histologically, and because cutaneous sarcoid is often associated with systemic involvement, the diagnosis of sarcoid should be strongly considered in patients with giant cell lichenoid dermatiti

 

点击下载:  PDF (5281KB)



返 回