Survival in Childhood Acute Lymphocytic Leukemia: Effect of Protocol and Place of Treatment
作者:
MeadowsAnna T.,
KramerShira,
HopsonRon,
LustbaderEdward,
JarrettPatricia,
EvansAudrey E.,
期刊:
Cancer Investigation
(Taylor Available online 1983)
卷期:
Volume 1,
issue 1
页码: 49-55
ISSN:0735-7907
年代: 1983
DOI:10.3109/07357908309040932
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The objective of this study was to determine the effect of place and type of initial treatment on survival from acute lymphocytic leukemia (ALL). Every one of the 327 children under 15 years of age diagnosed with ALL from 1970 to 1975 in a 31-county area designated the Greater Delaware Valley, were studied. Treatment according to protocol was associated with improved survival, yielding a 4 year survival of 60% vs 19% for nonprotocol treated patients (p<0.001). There was also a significantly improved survival rate among patients treated in a cancer center, especially for those with a low white blood count (WBC) at diagnosis. The prognostic importance of WBC, age, and sex was confirmed.
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