Fatal Phenytoin‐Related Toxic Epidermal Necrolysis: Case Report
作者:
Daniel Kelly,
Donald Hope,
期刊:
Neurosurgery
(OVID Available online 1989)
卷期:
Volume 25,
issue 6
页码: 976-978
ISSN:0148-396X
年代: 1989
出版商: OVID
关键词: Phenytoin;Posttraumatic epilepsy;Toxic epidermal necrolysis
数据来源: OVID
摘要:
&NA;Toxic epidermal necrolysis is a rare but often fatal hypersensitivity reaction to numerous agents, including most anticonvulsants. The authors present a case of fatal phenytoin‐related toxic epidermal necrolysis in a patient who was given prophylactic anticonvulsant therapy after he sustained a moderately severe closed head injury. The typical course and current management of toxic epidermal necrolysis are reviewed, as are the indications for the prophylaxis of posttraumatic epilepsy. (Neurosurgery25:976‐978, 1989)
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