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Liver Transglutaminases and Vitamin-A Deficiency in Hairless Mice

 

作者: N. Savouré,   C. Nio,   M. Maudet,   M. Nicol,  

 

期刊: Annals of Nutrition and Metabolism  (Karger Available online 1996)
卷期: Volume 40, issue 1  

页码: 52-60

 

ISSN:0250-6807

 

年代: 1996

 

DOI:10.1159/000177896

 

出版商: S. Karger AG

 

关键词: Liver transglutaminases;Vitamin-A deficiency;Hairless mice

 

数据来源: Karger

 

摘要:

In hairless mice, a moderate vitamin-A deficiency, without any clinical signs or weight changes, reduces the activity of soluble cytoplasmic hepatic transglutaminase without affecting the membrame form of the enzyme. This attack of soluble transglutaminase appears to be a biological marker of early deficiency. The relations between this disturbance and the hepatocyte sensitivity to aggressors at this stage are discussed.

 

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