Unruptured Intracranial Aneurysms: An Assessment of the Annual Risk of Rupture Based on Epidemiological and Clinical Data
作者:
RosenørnJarl,
EskesenVagn,
SchmidtKaare,
期刊:
British Journal of Neurosurgery
(Taylor Available online 1988)
卷期:
Volume 2,
issue 3
页码: 369-377
ISSN:0268-8697
年代: 1988
DOI:10.3109/02688698809001008
出版商: Taylor&Francis
关键词: Cerebral aneurysms;incidence;intracranial aneurysms;prevalence;subarachnoid haemorrhage
数据来源: Taylor
摘要:
From autopsy and neuroradiological studies a maximum prevalence of unruptured intracranial aneurysms (UA) of 0.5% in the general population is revealed. Studies concerning the incidence of aneurysmal subarachnoid haemorrhage (SAH) revealed 10 cases per 100,000 inhabitants per year. From these epidemiological parameters a minimum annual risk of 2% of rupture of an UA is calculated. It is in accordance with clinical studies, which also demonstrated an annual risk of UA rupture of at least 2%. No critical size of the UA predisposing to rupture has been found. Operation on diagnosed UA is recommended because of the serious prognosis after aneurysmal SAH (morbidity 20%-25% and mortality 50%-60%) and because the morbidity (4%) and the mortality (0%) after operative treatment of UA are very low.
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