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Unruptured Intracranial Aneurysms: An Assessment of the Annual Risk of Rupture Based on Epidemiological and Clinical Data

 

作者: RosenørnJarl,   EskesenVagn,   SchmidtKaare,  

 

期刊: British Journal of Neurosurgery  (Taylor Available online 1988)
卷期: Volume 2, issue 3  

页码: 369-377

 

ISSN:0268-8697

 

年代: 1988

 

DOI:10.3109/02688698809001008

 

出版商: Taylor&Francis

 

关键词: Cerebral aneurysms;incidence;intracranial aneurysms;prevalence;subarachnoid haemorrhage

 

数据来源: Taylor

 

摘要:

From autopsy and neuroradiological studies a maximum prevalence of unruptured intracranial aneurysms (UA) of 0.5% in the general population is revealed. Studies concerning the incidence of aneurysmal subarachnoid haemorrhage (SAH) revealed 10 cases per 100,000 inhabitants per year. From these epidemiological parameters a minimum annual risk of 2% of rupture of an UA is calculated. It is in accordance with clinical studies, which also demonstrated an annual risk of UA rupture of at least 2%. No critical size of the UA predisposing to rupture has been found. Operation on diagnosed UA is recommended because of the serious prognosis after aneurysmal SAH (morbidity 20%-25% and mortality 50%-60%) and because the morbidity (4%) and the mortality (0%) after operative treatment of UA are very low.

 

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