The predominant site of bleeding intestinal angiodysplasia in elderly patients will be the cecum or ascending colon, but recent experience in the Yale-Affiliated Gastroenterology Program in 1 year indicates that elderly patients may have bleeding acquired angiodysplasia (AD) confined to the small intestine only. A review of the literature confirms that symptomatic small intestinal AD is infrequent and occurs at an average age of 32 years in some series. Five patients with symptomatic small intestinal AD diagnosed during 1981 at Yale were older, with an average of 62 years. Three of the five cases (all female) had lesions in the duodenum, with two (males) having lesions in the ileum. Noncolonic AD in the elderly may be acquired during life, as in the classic situation in the right colon, but may be difficult to distinguish clinically and pathologically from the vascular lesions of hereditary hemorrhagic telangiectasia.