Development of the dermatome pattern in the limb
作者:
John C. McLachlan,
期刊:
Clinical Anatomy
(WILEY Available online 1990)
卷期:
Volume 3,
issue 1
页码: 41-49
ISSN:0897-3806
年代: 1990
DOI:10.1002/ca.980030106
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: nerves;innervation;embryo
数据来源: WILEY
摘要:
AbstractAn erroneous view of early nerve development in human limbs is presented in many medical embryology and neuroanatomy textbooks. The early limb bud is described as having segmental dermatome stripes running across it, which later reorganize to form the adult pattern. In fact, the nerves grow first into a plexus, which they later leave to supply fields very similar to those in the adult. Since this error may have clinical consequences, in that it gives a false view of how anomalies are likely to arise, its source is identified and its propagation through the literature is traced. A brief review of the most recent findings concerning the mechanisms by which nerve patterns are established in vertebrate limbs is also given.
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