Comparative in Vitro Activity of Augmentin Against Community and Hospital-Acquired Gram-Negative Bacteria
作者:
GlupczynskiY.,
McgillavryG.,
YourassowskyE.,
期刊:
Acta Clinica Belgica
(Taylor Available online 1988)
卷期:
Volume 43,
issue 2
页码: 109-114
ISSN:1784-3286
年代: 1988
DOI:10.1080/17843286.1988.11717917
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The susceptibility of 841 unselectcd, gramnegative bacterial isolates to augmentin, an amoxycillin/clavulanic acid formulation, was examined and compared with their sensitivity to other antibiotics. Susceptibility was measured using a disk diffusion procedure. Augmentin showed a high degree of activity against the folates tested. Overall rates of sensitivity, intermediate sensitivity, and resistance to augmentin among theEnlerobacleriaceaewere 81.6%, 7.6%, and 10.8%, respectively. As expected, a considerably higher degree of resistance occured to ampicillin (58.4 %). The antibacterial pattern augmentin compared favourably with that of the second-generation cephalosporin, cefuroxime. These results indicate that augmentin is likely to be clinically active against a conquerable number of community and hospital-acquired gram-negative strains.
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