ABSTRACTA clinical study comparing the sensitivity of the radionuclide skeletal survey to the radiographic skeletal survey and random iliac crest bone marrow aspiration in detecting metastatic disease in children with neurogenic tumors is presented. No false negative bone images for metastases were obtained during the initial evaluation. Uptake of tracer in the primary tumor was a frequent finding. The radionuclide survey is recommended in the initial evaluation of neurogenic tumors.