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A Retrospective Analysis of Tissue-Fixed Immunoreactants from Skin Biopsies Maintained in Michel’s Medium

 

作者: Vaughan Jones,   J. Salas,   J.A. McGrath,   I. Palmer,   B.S. Bhogal,   M.M. Black,  

 

期刊: Dermatology  （Karger Available online 1994）
卷期: Volume 189, issue 1  

页码: 131-132

 

ISSN:1018-8665

 

年代: 1994

 

DOI:10.1159/000246955

 

出版商: S. Karger AG

 

关键词: Michel’s medium;Immunofluorescence;Pemphigoid;Pemphigus;Lupus erythematosus;Dermatitis herpetiformis

 

数据来源: Karger

 

摘要:

656 skin biopsies with positive direct immunofluorescence from the UK and overseas were studied over a 2-year period. The length of time biopsies had remained in Michel’s medium at pH 7.0 in various diseases (pemphigoid, pemphigus, linear IgA disease, epidermolysis bullosa acquisita, lupus erythematosus, vasculitis, amyloid, lichen planus and dermatitis herpetiformis) was analysed. We concluded that direct immunofluorescence remained positive at 6 months and that Michel’s medium is a reliable long-term maintenance medium for skin biops

 

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