Criteria for Pulmonary and Respiratory Failure in COPD Patients – A Theoretical Study Based on Clinical Data
作者:
Yoshikazu Kawakami,
Tadashi Irie,
Fujiya Kishi,
期刊:
Respiration
(Karger Available online 1982)
卷期:
Volume 43,
issue 6
页码: 436-443
ISSN:0025-7931
年代: 1982
DOI:10.1159/000194515
出版商: S. Karger AG
关键词: Pulmonary gas exchange;Tissue hypoxia;Gas exchange efficiency
数据来源: Karger
摘要:
In 58 patients with chronic obstructive pulmonary disease, pulmonary gas exchange efficiency was assessed by the ratio: arterial to mixed venous PO2 difference (efficient part) versus alveolar to mixed venous POa difference (driving pressure for O2 transport). Patients with PaO2, below 75 mm Hg had a ratio lower than 50%. Patients with PaO, below 60 mm Hg had lower values for arterial to mixed venous O2 content difference and higher blood lactic acid concentration than patients with PaO2 over 60 mm Hg. Arterial to mixed venous PO2 difference decreased linearly against PaO2 till PaO2 reached 60 mm Hg from which the difference began to attenuate.These figures in PaO2 are in close agreement with the criteria for pulmonary failure presented by the Ciba guest symposium (PaO2 below 75 mm Hg) and for respiratory failure by the National Heart, Lung and Blood Institute (PaO, below 60 mm Hg).
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