Serum Coenzyme Q10 in Uremic Patients on Chronic Hemodialysis
作者:
Luigi Triolo,
Silvio Lippa,
Alessandro Oradei,
Pasquale De Sole,
Roberto Mori,
期刊:
Nephron
(Karger Available online 1994)
卷期:
Volume 66,
issue 2
页码: 153-156
ISSN:1660-8151
年代: 1994
DOI:10.1159/000187793
出版商: S. Karger AG
关键词: Coenzyme Q;Vitamin E;Uremia;Hemodialysis
数据来源: Karger
摘要:
In a group of 48 chronic hemodialysis patients, serum levels of coenzyme Q10 (CoQ) have been measured and appeared abnormally low in 62% of cases. Figures were positively correlated to those of serum vitamin E (vit E), although the latter were within a normal range. The chronic hemodialysis (CHD) patients with normal serum values of CoQ exhibited higher blood triglycerides. Pathologically low levels of serum vit E were found only in uremic subjects on conservative regimen with dietary restrictions and low compliance to protein-caloric intake. The reduced CoQ levels may contribute to the defective serum antioxidant activity and the increased peroxidative damage in uremic patients on CHD.
点击下载:
PDF
(758KB)
返 回