The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization
作者:
M. Egashira,
D. Kitamura,
T. Watanabe,
N. Niikawa,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1996)
卷期:
Volume 72,
issue 2-3
页码: 175-176
ISSN:1424-8581
年代: 1996
DOI:10.1159/000134179
出版商: S. Karger AG
数据来源: Karger
摘要:
The human HSI gene (HCLS1, hematopoietic cell-specific Lyn substrate 1) expressed in human hematopoietic cells encodes a major substrate of protein-tyrosine kinase, p75HS1. This intracellular protein is involved in the signal transduction pathways that initiate at the antigen receptors of both B and T lymphocytes. Fluorescence in situ hybridization using a 2.0-kb cDNA and an 8.0-kb genomic DNA clone of HCLS1 as probes revealed that the gene maps to 3q13.
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