Restricted expression of a human T cell lineage membrane antigen
作者:
Marion M. Roberts,
Melvyn F. Greaves,
期刊:
European Journal of Immunology
(WILEY Available online 1980)
卷期:
Volume 10,
issue 1
页码: 46-52
ISSN:0014-2980
年代: 1980
DOI:10.1002/eji.1830100110
出版商: WILEY‐VCH Verlag GmbH
数据来源: WILEY
摘要:
AbstractAn antiserum raised against human fetal and childhood thymocytes (anti‐Thy) and absorbed with peripheral lymphocytes (tonsil) detected an antigen(s) shared by thymocytes, T cell‐acute leukemias, activated peripheral T cells and a subset of peripheral T cells. The antigen was expressed by the negative circulating T cell subset after mitogen activation of that separated population. The antigen was shown to be separate from the E rosette receptor, another anti‐T cell serum detected antigen, and β2‐microglobulin; its expression was not related to a particular phase of the cell cycle. The results suggest that the antigen is expressed by T cells only under certain maturational and proliferative co
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