Protection by iron salts against sporidesmin intoxication in sheep
作者:
R. Munday,
E. Manns,
期刊:
New Zealand Veterinary Journal
(Taylor Available online 1989)
卷期:
Volume 37,
issue 2
页码: 65-68
ISSN:0048-0169
年代: 1989
DOI:10.1080/00480169.1989.35562
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A number of iron compounds have been shown to protect sheep against the harmful effects of the facial eczema toxin, sporidesmin. Various salts were found to be effective; the oxidation state of the metal was not important although water-solubility did appear to be a prerequisite for prophylactic activity. The effect of iron salts was additive with that of zinc, and it is suggested that the protective action of these compounds results from their ability to inhibit the absorption of copper, consistent with the previously-proposed freeradical mechanism for sporidesmin toxicity.
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