This paper reports experimental results from the use of pure natural honey for drag reduction in capillary tubes, with particular reference to biomedical engineering. The effects of the capillary tube diameter, the Reynolds numbers, concentration percentages, and honey type on the drag reduction were investigated. The maximum drag reduction obtained in this investigation is very much dependent on both the diameter of the capillary tubes and the concentration of the honey. Maximum drag reductions of 17.1%, 46.9%, and 37.3% at concentrations of 1000 ppm were obtained for the tube diameters of 1 mm, 1.3 mm, and 1.5 mm, respectively. Increasing the concentrations to 2000 ppm gave maximum reductions of 43%, 36.5%, and 50% for the tube diameters of 2 mm, 2.5 mm, and 3 mm, respectively.