Potentiometric Non Aqueous Determination of Glaphenine Hydrochloride and in Its Pharmaceutical Formulations
作者:
MostafaS. Tawakkol,
MohamedE. Mohamed,
期刊:
Analytical Letters
(Taylor Available online 1981)
卷期:
Volume 14,
issue 10
页码: 763-770
ISSN:0003-2719
年代: 1981
DOI:10.1080/00032718108055480
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A direct nonaqueous potentiometric determination of glaphenine hydrochloride and glaphenine authentic compounds and in their pharmaceutical formulations, namely glifanan suppositories, glifanan and adalgur tablets(R)is developed. The method involves the titration with 0.1N aceteous perchloric acid after the addition of mercuric acetate in case of hydrochloride salts, using a combined glass electrode. The results of the method were compared with those of the spectrophotometric1and the alkalimetric2procedures. The method can be adopted for quantities ranging between 50 and 500 mg with an accuracy of 102 ± 1.1, 98.8 ± 0.4 and 101.2 ± 0.5 for glifanan suppositories, glifanan tablets and adalgur tablets respectively.
点击下载:
PDF (223KB)
返 回